Tag: Pashley DH

Effects of calcium silicate-based materials on the flexural properties of dentin

ABSTRACT INTRODUCTION: Prolonged exposure of root dentin to calcium hydroxide alters the fracture resistance of dentin. Calcium silicate-based materials (CSMs) used in endodontics release calcium hydroxide on setting. This study examined whether prolonged contact of dentin with CSMs adversely affects its mechanical properties. METHODS: Dentin beams prepared from extracted human molars (7 × 3 × […]

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Effects of an experimental calcium aluminosilicate cement on the viability of murine odontoblast-like cells

ABSTRACT INTRODUCTION: Quick-setting calcium aluminosilicate cement with improved washout resistance is a potential substitute for calcium silicate cements in endodontics. This study examined the effect of an experimental calcium aluminosilicate cement (Quick-Set; Primus Consulting, Bradenton, FL) on the viability of odontoblast-like cells. METHODS: The biocompatibility of Quick-Set and white ProRoot MTA (WMTA; Dentsply Tulsa Dental […]

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In vitro osteogenic/dentinogenic potential of an experimental calcium aluminosilicate cement

ABSTRACT INTRODUCTION: Calcium aluminosilicate cements are fast-setting, acid-resistant, bioactive cements that may be used as root-repair materials. This study examined the osteogenic/dentinogenic potential of an experimental calcium aluminosilicate cement (Quick-Set) by using a murine odontoblast-like cell model. METHODS: Quick-Set and white ProRoot MTA (WMTA) were mixed with the proprietary gel or deionized water, allowed to […]

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In vitro biocompatibility and oxidative stress profiles of different hydraulic calcium silicate cements

ABSTRACT INTRODUCTION: MTA Plus is a new calcium silicate cement with unknown cytotoxicity characteristics. The objectives of this study were to examine the effect of MTA Plus on the viability, apoptosis/necrosis profile, and oxidative stress levels of rat odontoblastlike cells. METHODS: MDPC-23 cells were exposed to gray and white MTA Plus (GMTAP, WMTAP), gray and […]

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In Vitro Biocompatibility and Oxidative Stress Profiles of Different Hydraulic Calcium Silicate Cements

Abstract Introduction: MTA Plus is a new calcium silicate cement with unknown cytotoxicity characteristics. The objectives of this study were to examine the effect of MTA Plus on the viability, apoptosis/necrosis profile, and oxidative stress levels of rat odontoblast-like cells. Methods: MDPC-23 cells were exposed to gray and white MTA Plus (GMTAP, WMTAP), gray and […]

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In Vitro Osteogenic/Dentinogenic Potential of an Experimental Calcium Aluminosilicate Cement

Abstract Introduction: Calcium aluminosilicate cements are fast-setting, acid-resistant, bioactive cements that may be used as root-repair materials. This study examined the osteogenic/dentinogenic potential of an experimental calcium aluminosilicate cement (Quick-Set) by using a murine odontoblast-like cell model. Methods: Quick-Set and white ProRoot MTA (WMTA) were mixed with the proprietary gel or deionized water, allowed to […]

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Effects of an Experimental Calcium Aluminosilicate Cement on the Viability of Murine Odontoblast-like Cells

Abstract Introduction: Quick-setting calcium aluminosilicate cement with improved washout resistance is a potential substitute for calcium silicate cements in endodontics. This study examined the effect of an experimental calcium aluminosilicate cement (Quick-Set; Primus Consulting, Bradenton, FL) on the viability of odontoblast-like cells. Methods: The biocompatibility of Quick-Set and white ProRoot MTA (WMTA; Dentsply Tulsa Dental […]

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Effects of Calcium Silicate-based Materials on Collagen Matrix Integrity of Mineralized Dentin

Introduction: Calcium silicate–based materials (CSMs) are used in various endodontic procedures. The present study examined whether prolonged contact of mineralized dentin with recently commercialized versions of these materials adversely affects dentin collagen matrix integrity. Methods: Dentin slabs prepared from extracted human third molars (7  3  0.3 mm) were divided into 3 groups on […]

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Effects of Calcium Silicate–based Materials on the Flexural Properties of Dentin

Introduction: Prolonged exposure of root dentin to calcium hydroxide alters the fracture resistance of dentin. Calcium silicate–based materials (CSMs) used in endodontics release calcium hydroxide on setting. This study examined whether prolonged contact of dentin with CSMs adversely affects its mechanical properties.  (J Endod. 2012 May;38(5):680-3. )  

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Remineralization of artificial dentinal caries lesions by biomimetically modified mineral trioxide aggregate

Abstract: Fluoride-releasing restorative materials are available for remineralization of enamel and root caries. However, remineralization of dentin is more difficult than remineralization of enamel due to the paucity of apatite seed crystallites along the lesion surface for heterogeneous crystal growth. Extracellular matrix proteins play critical roles in controlling apatite nucleation/growth in collagenous tissues. This study […]

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