NeoSEALERTM Flo is a bioactive bioceramic root canal sealer with superior handling properties, promoting hydroxyapatite formation to trigger the healing process. Unlike conventional sealers, NeoSEALER Flo is biocompatible, antimicrobial1, dimensionally stable and RESIN-FREE.


NeoSEALER Flo is packaged with our exclusive Flex Flo Tips™ to minimize product waste by 81% at no additional cost.


Features & Benefits
Bioactive bioceramic
Versatile – Optimized for both warm vertical and single cone obturation techniques.

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See more on Flex Flo TipsTM

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  • Obturation and sealing of root canals.
  • Features & Benefits

      Formulated With More Bioactive Cement Than Original Bioceramic Sealer2

    • NeoSEALER Flo is thoughtfully designed to promote setting and maximize bioactivity.
    • Promotes the formation of hydroxyapatite on the surface to seal and support healing through the release of calcium and hydroxide ions.
    • Biocompatible, non-cytotoxic, non-genotoxic, initially high in pH (alkaline/basic), which has shown to be antimicrobial in-vitro1.
    • Optimized for both warm vertical and single cone obturation techniques

    • Streamline your inventory with one product suitable for both warm vertical and single cone obturation techniques for maximum efficiency and savings.
    • Resin-Free

    • Resin-free for maximum bioactivity and biocompatibility.
    • Non-Staining

    • Won’t discolor teeth – EVER. NaOCI won’t cause discoloration.
    • Dimensionally stable

    • Unlike resin-based sealers, NeoSEALER Flo is dimensionally stable.
    • High pH

    • Initially high in pH (alkaline/basic), which has shown to be antimicrobial in-vitro1.
    1NeoSEALER Flo is initially high in pH (alkaline/basic) when applied. Literature has shown such products to be antimicrobial in-vitro.
    The anti-microbial effect against enterococcus faecalis and the compressive strength of two types of mineral trioxide aggregate mixed with sterile water or 2% chlorhexidine liquid.
    Holt DM, Watts JD, Beeson TJ, Kirkpatrick TC, Rutledge RE. J Endod. 2007 Jul;33(7):844-7.

    2 NeoSEALER Flo contains 6% more bioactive cement by weight compared to EndoSequence BC Sealer (in-house data obtained through XRD analysis)

    Flex Flo Tip

      You no longer need to buy the minimal waste tips at a separate cost.

    Every NeoSEALER Flo kit is packaged with 20 or 40 minimal waste Flex Flo Tips™ designed to:

  • Designed for 81% less waste than conventional tips
  • Integrated stopper for accuracy of placement
  • 25.5 gauge flexible tip to reach deep into smaller canals

  • Available in:

  • Flex Flo Tips (20/pack)
  • Flex Flo Tips (40/pack)
    A Randomized Clinical Trial of NeoMTA Plus in Primary Molar Pulpotomies.
    The purpose of this study was to compare the success of pulpotomies in primary molars using a new type of mineral trioxide aggregate (MTA; NeoMTA Plus) with a conventional MTA (ProRoot MTA) as a pulpotomy medicament in primary molars.
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    Bioactive tri/dicalcium silicate cements for treatment of pulpal and periapical tissues.
    This review emphasizes research on how these materials have conformed to international standards for dental materials ranging from biocompatibility (ISO 7405) to conformance as root canal sealers (ISO 6876).
    Read more
    Histology of NeoMTA Plus and Quick-Set2 in Contact with Pulp and Periradicular Tissues in a Canine Model.
    The purpose of this study was to compare the healing of pupal and periapical tissues in dogs after exposure to NeoMTA Plus and Quick-Set2 after pulpotomy and root-end surgery procedures.
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    Dentinal Tubule Penetration of Tricalcium Silicate Sealers.
    Smaller particle size and easier handling properties have allowed the advent of tricalcium silicate sealers. The objective of this study was to measure the tubule penetration with these sealers using continuous wave (CW) and single-cone (SC) obturation techniques.
    Read more

    Unlike inert resin and ZOE materials, MTA provides state-of-the-art Bioactive technology
    to promote bioactivity and support healing.

    After placement of MTA in the tooth, body fluids infiltrate the material to cause setting.

    During this process, calcium and hydroxide ions are released from the MTA, promoting hydroxyapatite (HA) formation on the MTA surfaces.

    When HA coats the surface, it hides the underlying MTA to minimize foreign body reactions and support healing responses of the pulpal or periapical tissue.

    Calcium phosphate precipitated crystals scattered on the hydrated tricalcium silicate cement surface1.

    High magnification image of the calcium phosphate crystals1.

    MTA-Based Bioactivity
    Hydroxyapatite forms to ensure Bioactive sealing.

    Dr. Brett Gilbert, founder of Access Endo interview NeoPUTTY inventor Dr Carolyn Primus PhD

    Additional information

    NeoSEALER Flo Kit Size

    Starter Kit – 2.2gm, Professional Kit – 4.4gm


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