NeoSEALER® Flo is a bioactive bioceramic root canal sealer with superior handling properties, promoting hydroxyapatite formation to support the healing process. Unlike conventional sealers, NeoSEALER Flo is biocompatible, antimicrobial1, dimensionally stable and RESIN-FREE.



Dental Advisor 2022 Top Award • Endodontic Sealer
NeoSEALER® Flo is a hit! Read the reviews.


NeoSEALER Flo is packaged with our exclusive Flex Flo Tips™ to minimize product waste by 81% at no additional cost.


Features & Benefits
Bioactive bioceramic
Versatile – Optimized for both warm vertical and single cone obturation techniques.

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See more on Flex Flo TipsTM

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  • Obturation and sealing of root canals.

Features & Benefits

Formulated With More Bioactive Cement Than Original Bioceramic Sealer2

    • NeoSEALER Flo is thoughtfully designed to promote setting and maximize bioactivity.
    • Promotes the formation of hydroxyapatite on the surface to seal and support healing through the release of calcium and hydroxide ions.
    • Biocompatible, non-cytotoxic, non-genotoxic, initially high in pH (alkaline/basic), which has shown to be antimicrobial in-vitro1.

Optimized for both warm vertical and single cone obturation techniques

    • Streamline your inventory with one product suitable for both warm vertical and single cone obturation techniques for maximum efficiency and savings.


    • Resin-free for maximum bioactivity and biocompatibility.


    • Won’t discolor teeth – EVER. NaOCI won’t cause discoloration.

Dimensionally stable

    • Unlike resin-based sealers, NeoSEALER Flo is dimensionally stable.

High pH

  • Initially high in pH (alkaline/basic), which has shown to be antimicrobial in-vitro1.
1NeoSEALER Flo is initially high in pH (alkaline/basic) when applied. Literature has shown such products to be antimicrobial in-vitro.
The anti-microbial effect against enterococcus faecalis and the compressive strength of two types of mineral trioxide aggregate mixed with sterile water or 2% chlorhexidine liquid.
Holt DM, Watts JD, Beeson TJ, Kirkpatrick TC, Rutledge RE. J Endod. 2007 Jul;33(7):844-7.

2 NeoSEALER Flo contains 6% more bioactive cement by weight compared to EndoSequence BC Sealer (in-house data obtained through XRD analysis)

Flex Flo Tip

You no longer need to buy the minimal waste tips at a separate cost.

Every NeoSEALER Flo kit is packaged with 20 or 40 minimal waste Flex Flo Tips™ designed to:
  • Designed for 81% less waste than conventional tips
  • Integrated stopper for accuracy of placement
  • 25.5 gauge flexible tip to reach deep into curved and small canals.

Available in:


A Randomized Clinical Trial of NeoMTA Plus in Primary Molar Pulpotomies.
The purpose of this study was to compare the success of pulpotomies in primary molars using a new type of mineral trioxide aggregate (MTA; NeoMTA Plus) with a conventional MTA (ProRoot MTA) as a pulpotomy medicament in primary molars.
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Bioactive tri/dicalcium silicate cements for treatment of pulpal and periapical tissues.
This review emphasizes research on how these materials have conformed to international standards for dental materials ranging from biocompatibility (ISO 7405) to conformance as root canal sealers (ISO 6876).
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Histology of NeoMTA Plus and Quick-Set2 in Contact with Pulp and Periradicular Tissues in a Canine Model.
The purpose of this study was to compare the healing of pupal and periapical tissues in dogs after exposure to NeoMTA Plus and Quick-Set2 after pulpotomy and root-end surgery procedures.
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Dentinal Tubule Penetration of Tricalcium Silicate Sealers.
Smaller particle size and easier handling properties have allowed the advent of tricalcium silicate sealers. The objective of this study was to measure the tubule penetration with these sealers using continuous wave (CW) and single-cone (SC) obturation techniques.
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Dr. Brett Gilbert, founder of Access Endo interview NeoPUTTY inventor Dr Carolyn Primus PhD

Additional information

NeoSEALER Flo Kit Size

2.2gm Kit, 4.4gm Kit


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NeoMTA Plus is a stainproof, tricalcium silicate-based bioactive cement that can be used universally for vital pulp and other endodontic indications in primary and permanent teeth. NeoMTA Plus is a bioceramic cement that triggers the healing process. With NeoMTA Plus, general dentists, pediatric dentists, and endodontists now have a superior and reasonably priced bioceramic. Dentists praise the multi-use NeoMTA Plus because it mixes more smoothly, is easier to dispense and the unique gel enables more stable placement, washout resistance and faster clinical setting.

New, stain-free light color:

Ideal for pediatric dentistry—won’t discolor teeth
Liquids such as sodium hypochlorite won’t cause discoloration

Multiple indications:

Pulp-capping to base/liner
Pulpotomies to apexification
Sealer to perforation repair
Root-end filling to resorption


Inhibits bacterial growth* *Tested in vitro. Not a disinfectant

Grey MTA Plus is a bioceramic tricalcium silicate-based Dental Cement, which is slightly more radiopaque than (white) MTA. The light silvery color of MTA Plus is visible during placement. Grey MTA Plus is indicated for both Vital Pulp Therapy and Endodontic procedures. General dentists and endodontists praise the multi-use Grey MTA Plus because it mixes more smoothly and is easier to dispense. The unique gel enables more stable placement, washout resistance and faster clinical setting.

Multiple indications:

Pulp-capping to Base/Liner
Pulpotomies to Apexification
Sealer to Perforation Repair
Root-end Filling to Resorption

New, light grey color:

More radiopaque than the leading white MTAs
Visible for precise placement
Inhibits bacterial growth in vitro of Staphylococcus aureus, Escherichia coli, Enterococcus faecalis, Pseudomonas aeruginosa.

Better mixing, handling and placement:

Finer powder mixes more easily and smoothly
Dispense as little as 0.1 gm
Unique gel for stable placement
Washout resistant
No special equipment required

Smart, convenient packaging:

Protects fine powder in desiccant-lined bottle
Easy to dispense powder as needed
Dropper-tip gel bottle minimizes waste