NuSmile Acquires Avalon Biomed

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NuSmile Acquires MTA Manufacturer Avalon Biomed

World leader in restorative dentistry expands bioceramic materials capabilities

HOUSTON, TEXAS, November 4, 2016—NuSmile Ltd. today announced its acquisition of substantially all of the assets of Avalon Biomed Inc., a leading designer and manufacturer of advanced mineral trioxide aggregate (MTA) products.
Avalon Biomed Inc. was founded in 2011 by Carolyn Primus, PhD, who holds both Masters and Doctorate degrees in Materials Science & Engineering. Dr. Primus has 10 patents in dentistry, including three for MTA-based products, to her credit, and has co-authored over 20 papers on bioactive dental cements. Avalon Biomed’s two key commercial products are NeoMTA Plus® and Grey MTA Plus®.

NeoMTA Plus and Grey MTA Plus are award-winning, bioceramic, tricalcium silicate-based bioactive cements that trigger hydroxyapatite formation and dentinal bridging to promote the healing process. These products have broad indications for pulpal and periapical tissue contact including root-end filling to resorption, sealer to perforation repair, pulp-capping to base/liner, and pulpotomies to apexification. Each product is non-cytotoxic, mixes smoothly, handles easily, and enables washout resistance and faster clinical setting.

NeoMTA Plus is a light-colored, stainproof MTA that can be used universally for vital pulp and other endodontic indications. Grey MTA Plus has a light silvery color and is slightly more radiopaque for endodontic use.

Dr. Primus will join the NuSmile team and will lead its research efforts in bioceramic materials. “We are excited to have Dr. Primus and Avalon Biomed as part of the NuSmile family,” said Diane Johnson Krueger, NuSmile founder and CEO. “Dr. Primus will continue to focus on developing state- of-the-art bioceramic medicaments for NuSmile, while the NuSmile team will ensure that we provide Avalon Biomed customers with the extraordinary customer care that NuSmile is famous for.”

“We are delighted to be part of the NuSmile family,” said Dr. Primus. “While we are proud of what we have been able to accomplish from an NIH SBIR grant in founding Avalon Biomed, and are confident that our greatest service to dental patients and clinicians lies ahead of us.”

According to Mark Binford, NuSmile SVP of New Product Development, NeoMTA Plus and Grey MTA Plus will continue to be marketed through Avalon Biomed’s global network of dental distributors, and through direct sales on Avalon Biomed’s website in the USA and Canada. He added, “We are committed to making sure that this transition is seamless for Avalon Biomed customers, NuSmile customers, and our distributors.”

NuSmile will continue to maintain the Avalon Biomed website at NuSmile’s recently enhanced website may be viewed at


About NuSmile
Founded in 1991 in Houston, Texas by Diane Johnson Krueger, NuSmile is the worldwide leader in pediatric esthetic restorative dentistry. Shortly after its founding, the company invented its first esthetic pediatric crown; more than 4 million have been used in restorations in the 25 years since. The company’s current offerings include the NuSmile ZR Zirconia crown system, featuring Try-In crowns to prevent saliva/blood contamination and NuSmile BioCem® BioActive Cement for exceptional bond strength and handling; NuSmile Signature Pre- veneered crowns; NuSmile SSC Pre-contoured crowns; and NuSmile NeoMTA® pulp therapy medicament. NuSmile prides itself on its passion for customer care, its unwavering commitment to research, and its unmatched support for American Academy of Pediatric Dentistry (AAPD), the International Association of Pediatric Dentistry (IAPD), the Canadian Academy of Pediatric Dentistry/Académie Canadienne de Dentisterie Pédiatrique (CAPD/ACPD), the Institute for Pediatric Dentistry (IPD) and several other organizations dedicated to the dental care of children and the dentists who serve them.

Media Contact
John Pohl
14th Floor Solutions, LLC

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NeoMTA Plus is a stainproof, tricalcium silicate-based bioactive cement that can be used universally for vital pulp and other endodontic indications in primary and permanent teeth. NeoMTA Plus is a bioceramic cement that triggers the healing process. With NeoMTA Plus, general dentists, pediatric dentists, and endodontists now have a superior and reasonably priced bioceramic. Dentists praise the multi-use NeoMTA Plus because it mixes more smoothly, is easier to dispense and the unique gel enables more stable placement, washout resistance and faster clinical setting.

New, stain-free light color:

Ideal for pediatric dentistry—won’t discolor teeth
Liquids such as sodium hypochlorite won’t cause discoloration

Multiple indications:

Pulp-capping to base/liner
Pulpotomies to apexification
Sealer to perforation repair
Root-end filling to resorption


Inhibits bacterial growth* *Tested in vitro. Not a disinfectant

Grey MTA Plus is a bioceramic tricalcium silicate-based Dental Cement, which is slightly more radiopaque than (white) MTA. The light silvery color of MTA Plus is visible during placement. Grey MTA Plus is indicated for both Vital Pulp Therapy and Endodontic procedures. General dentists and endodontists praise the multi-use Grey MTA Plus because it mixes more smoothly and is easier to dispense. The unique gel enables more stable placement, washout resistance and faster clinical setting.

Multiple indications:

Pulp-capping to Base/Liner
Pulpotomies to Apexification
Sealer to Perforation Repair
Root-end Filling to Resorption

New, light grey color:

More radiopaque than the leading white MTAs
Visible for precise placement
Inhibits bacterial growth in vitro of Staphylococcus aureus, Escherichia coli, Enterococcus faecalis, Pseudomonas aeruginosa.

Better mixing, handling and placement:

Finer powder mixes more easily and smoothly
Dispense as little as 0.1 gm
Unique gel for stable placement
Washout resistant
No special equipment required

Smart, convenient packaging:

Protects fine powder in desiccant-lined bottle
Easy to dispense powder as needed
Dropper-tip gel bottle minimizes waste